The 5-Second Trick For Ataxin-8 Protein
The neurologic phenotype in SCA8 BAC expansion although not BAC Regulate lines shown the pathogenicity on the (CTG-CAG)n growth. Moreover, the expression of noncoding (CUG)n enlargement ATXN8OS transcripts and the discovery of intranuclear polyglutamine inclusions prompt that SCA8 pathogenesis requires toxic attain-of-perform mechanisms at both the